General Toxicology Studies
Vivotecnia is a fully accredited GLP facility and conducts all studies to GLP standards, whether or not monitored by quality assurance. We use Instem’s Provantis ® platform for rapid and accurate data capture.
Our in-house processes are developed to ensure maximum efficiency, guaranteeing that you receive a high-quality report within a competitive timeframe. We also offer fast, reliable, conveniently tailored in-vivo screening studies to address your discovery needs.
We offer a range of monitored and unmonitored regulatory in vivo studies:
- Pharmacokinetics/toxicokinetics
- MTD and dose-range-finding
- Short- to long-term toxicology testing
- Rodents and nonrodent species
- Administration routes: enteral, parenteral, ocular, topical or others on request
- Inhalatory route:
- Liquid nebulizer
- Rotating-brush aerosol generator
- Tobacco-smoke aerosol generator
- Oral
- Intraperitoneal
- Intramuscular
- Vaginal
- Dermal
- Intradermal
- Subcutaneous
- Ocular
- Intravenous
- Inhalation
- Other (after setup)
- Rat
- Rabbit
- Nonhuman primate
- Mouse
- Dog
- Guinea pig
- Minipig
- Other
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PK/PD and Metabolism
During the drug discovery process, ADME (absorption, distribution, metabolism, and excretion) and PK studies are deemed necessary to evaluate bioavailability.
Inhalation
Inhalation toxicity studies are required to assess the exposure hazards of consumer products or to manufacturing workers.
Nonhuman primates
Our in-house veterinary team ensures that animal welfare is paramount and is committed to the principles of the 3Rs (replacement, reduction, refinement).